Identification of metabolic units induced by environmental signals

Identification of metabolic units induced by environmental signals

MOTIVATION Biological cells continually need to adapt the activity levels of metabolic functions to changes in their living environment. Although genome-wide transcriptional data have been gathered in a large variety of environmental conditions, the connections between the expression response to external changes and the induction or repression of specific metabolic functions have not been inves...

Shredding of Environmental Signals by Sediment Transport

Landscapes respond to climate, tectonic motions and sea level, but this response is mediated by sediment transport. Understanding transmission of environmental signals is crucial for predicting landscape response to climate change, and interpreting paleo-climate and tectonics from stratigraphy. Here we propose that sediment transport can act as a nonlinear filter that completely destroys (“shre...

Tipping points and early warning signals in the genomic composition of populations induced by environmental changes

We live in an ever changing biosphere that faces continuous and often stressing environmental challenges. From this perspective, much effort is currently devoted to understanding how natural populations succeed or fail in adapting to evolving conditions. In a different context, many complex dynamical systems experience critical transitions where their dynamical behaviour or internal structure c...

Studies on Bacteriophage and Metabolic Identification of Brucella Strains

Heavy Metal Induced Cell Necrosis: Involves Apoptosis Death Signals Initiated by Mitochondrial Injury

Introduction: Severe industrial diseases result from the hepatic accumulation of mercury, cadmium or chromium in humans and on the other hand cadmium and dichromate and mercuric salts may induce lung or kidney cancer. Acute or chronic CdCl2, HgCl2 or dichromate administration induces hepatic and nephrotoxicity in rodents. Oxidative stress is often cited as a possible cause of metal induced cell...